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    🔬 Peptide Manufacturing Process Overview

    Step Details
    🧱Solid-Phase Peptide Synthesis (SPPS) Peptides are synthesized step-by-step on an insoluble resin. Fmoc-protected amino acids are activated and coupled one at a time to build the peptide chain from the C-terminal to the N-terminal.
    🔄Deprotection and Coupling Cycles Each cycle includes removal of the Fmoc protecting group (usually with piperidine) followed by the next amino acid addition using activating agents like HBTU/HATU in DMF solution.
    ✂️Cleavage from Resin Once the sequence is complete, the peptide is cleaved from the resin using trifluoroacetic acid (TFA), which also removes side-chain protecting groups.
    🧊Crude Peptide Precipitation The peptide is precipitated from the cleavage solution by addition of cold ether or similar non-polar solvents to isolate it in solid form.
    ⚗️Acetate Salt Formation TFA residues are removed and the peptide is converted into an acetate salt using acetic acid or through ion-exchange desalting, improving peptide stability and reducing acidity.
    🧪Purification (RP-HPLC) The crude peptide is purified using reverse-phase high-performance liquid chromatography (RP-HPLC) to isolate the desired product and eliminate side-products, usually achieving ≥98% purity.
    ❄️Lyophilization The purified peptide is dissolved in a suitable buffer or water, frozen, and then subjected to vacuum drying. This results in a lyophilized (freeze-dried) powder that is chemically stable and easy to store.
    📊Analytical Characterization Final product quality is confirmed using analytical methods such as mass spectrometry (MS), analytical HPLC, and NMR to ensure proper identity, purity, and molecular integrity.

    🔬 Peptide Product Library

    Compound Name Summary Details
    Tirzepatide Acetate Dual GIP/GLP-1 agonist; 39-amino acid peptide View
    Semaglutide Acetate GLP-1 receptor agonist for metabolic research View
    Cagrilintide Acetate Amylin analogue for appetite regulation research View
    CagriSema Cagrilintide + Semaglutide co-agonist View
    Retatrutide Acetate Triple agonist (GLP-1/GIP/Glucagon) peptide View
    Mazdutide Acetate GLP-1/Glucagon dual receptor agonist View
    Survodutide Acetate Glucagon/GLP-1 dual receptor agonist peptide View
    AOD-9604 Acetate Fragment of HGH; stimulates lipolysis View
    BPC-157 Acetate Pentadecapeptide with regenerative potential View
    TB-500 Acetate Synthetic thymosin beta-4 for repair and recovery View
    Wolverine Blend BPC-157 + TB-500 for tissue regeneration View
    Ipamorelin Acetate Selective GH secretagogue View
    CJC-1295 Acetate Long-acting GHRH analog View
    MOD GRF (1-29) Acetate Short-acting GHRH analog View
    Tesamorelin Acetate GHRH analog; reduces visceral fat View
    Frag 176-191 Acetate Modified HGH fragment for fat loss research View
    GHRP-2 Acetate GH-releasing peptide with appetite stimulation View
    GHRP-6 Acetate GH-releasing peptide; stimulates ghrelin receptor View
    Melanotan I Acetate α-MSH analog for skin pigmentation studies View
    Melanotan II Acetate α-MSH analog with libido-enhancing effects View
    PT-141 Acetate Melanocortin receptor agonist for sexual function View
    GHK-Cu Acetate Copper peptide for wound healing and cosmetic use View
    Epitalon Acetate Synthetic tetrapeptide for telomerase activation View
    NAD+ (Nicotinamide Adenine Dinucleotide) Supports mitochondrial and metabolic function View
    MOTS-c Acetate Mitochondrial-derived peptide for metabolic health View
    Semax Acetate Synthetic peptide for cognitive enhancement View
    Selank Acetate Anxiolytic peptide with nootropic potential View
    Adipotide (FTPP) Targeted apoptosis of adipose vasculature View

    Comparative studies of GLP-1 peptides and trials data: CLICK HERE