GHRP-6 Acetate

Description

GHRP-6 Acetate

Chemical Name: Growth Hormone Releasing Peptide-6 (GHRP-6) Acetate
Molecular Formula: C₄₆H₅₆N₁₂O₆
Molecular Weight: ~873.01 g/mol
CAS Number: 87616-84-0

Sequence:
His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂

Structural Characteristics:
GHRP-6 is a synthetic hexapeptide and potent agonist of the ghrelin receptor (GHS-R1a). It stimulates endogenous growth hormone release through a mechanism independent of GHRH. Compared to GHRP-2, GHRP-6 is also known to enhance appetite via hypothalamic activity.

Mechanism of Action (Research Context):
GHRP-6 binds to the ghrelin receptor to promote GH secretion and influence appetite-regulating pathways. Research applications include:

• GH release and endocrine axis research
• Cachexia, muscle wasting, and metabolic syndrome models
• Appetite stimulation and energy homeostasis investigations

Synthesis and Quality Control:

• Produced via solid-phase peptide synthesis (SPPS)
• Purified to ≥98% by HPLC
• Identity confirmed by Mass Spectrometry (MS)

Product Details:

• Form: Lyophilized acetate salt
• Appearance: White to off-white powder

Solubility:
GHRP-6 Acetate is soluble in sterile water, dilute acetic acid, or aqueous buffers at pH 5–7.

Storage & Handling:

• Store lyophilized powder at –20°C, protected from light and moisture.
• After reconstitution, refrigerate at 2–8°C for up to 30 days.
• For long-term storage, aliquot and freeze at –20°C.
• Avoid repeated freeze-thaw cycles.

Disclaimer:
For research use only. Not intended for human or veterinary use. Not for diagnostic or therapeutic applications.