Semax Acetate
$59.19
Semax Acetate is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from the adrenocorticotropic hormone (ACTH 4–10) fragment, engineered for research into neuroprotection, cognitive enhancement, and neurotrophic regulation. Semax has been shown in preclinical models to modulate BDNF expression, influence dopaminergic and serotonergic activity, and support investigations into ischemic tolerance, synaptic plasticity, and stress adaptation.
Supplied as a lyophilized acetate salt, Semax Acetate is optimized for sterility, stability, and extended shelf life. Provided in a 3mL vial, this peptide is ideal for research involving neurogenesis, CNS homeostasis, and memory or attention-related pathways.
Solubility: Semax Acetate is soluble in sterile water, dilute acetic acid, or aqueous buffers at pH 5–7.
For laboratory research use only. Not for human or veterinary applications.
Description
Semax Acetate
Chemical Name: Met-Glu-His-Phe-Pro-Gly-Pro (Semax) Acetate
Molecular Formula: C₃₇H₅₁N₉O₁₀
Molecular Weight: ~831.87 g/mol
CAS Number: 80714-61-0
Sequence:
Met-Glu-His-Phe-Pro-Gly-Pro
Structural Characteristics:
Semax is a synthetic heptapeptide derivative of adrenocorticotropic hormone (ACTH 4-10), modified for enhanced metabolic stability and neuroactivity. It is classified as a nootropic and neuroprotective agent in research settings, with potential roles in regulating neuronal function, plasticity, and oxidative defense.
Mechanism of Action (Research Context):
Semax exhibits multiple neurobiological effects believed to involve modulation of:
- Brain-derived neurotrophic factor (BDNF) expression
- NMDA receptor signaling
- Antioxidant enzyme regulation and stress response
Research applications include:
- Cognitive enhancement and neuroprotection models
- Stroke, ischemia, and traumatic brain injury (TBI) studies
- Anxiety, depression, and neuroinflammation pathways
Synthesis and Quality Control:
- Produced via solid-phase peptide synthesis (SPPS)
- Purified by HPLC to ≥98%
- Verified by Mass Spectrometry (MS)
Product Details:
- Form: Lyophilized acetate salt
- Appearance: White to off-white powder
- Supplied in: 3mL sterile vial
Solubility & Reconstitution:
Semax Acetate is soluble in sterile water, dilute acetic acid, or aqueous buffers at pH 5–7.
- Swirl gently to dissolve; avoid vigorous agitation
- Protect reconstituted solution from oxidation and elevated pH
Storage & Handling:
- Store lyophilized powder at –20°C, away from moisture and light
- After reconstitution, refrigerate at 2–8°C for up to 30 days
- For extended storage, aliquot and freeze at –20°C
- Avoid repeated freeze-thaw cycles
Disclaimer:
For research use only. Not for human or veterinary use. Not for diagnostic or therapeutic applications.
Additional information
| Weight | .06 lbs |
|---|---|
| Dimensions | .5 × .5 × 1 in |
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