Selank Acetate

Description

Selank Acetate

Chemical Name: Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selank) Acetate
Molecular Formula: C₃₃H₅₇N₁₁O₉
Molecular Weight: ~751.88 g/mol
CAS Number: 129954-34-3

Sequence:
Thr-Lys-Pro-Arg-Pro-Gly-Pro

Structural Characteristics:
Selank is a synthetic heptapeptide analog of tuftsin, engineered for enhanced neuropsychotropic and immunomodulatory activity. It exhibits stable bioactivity in CNS-related models and has been studied for its anxiolytic, nootropic, and anti-inflammatory properties.

Mechanism of Action (Research Context):
Selank modulates the expression of brain-derived neurotrophic factor (BDNF), affects monoamine neurotransmitter levels, and interacts with GABAergic and serotonergic systems. Research applications include:

• Anxiety and stress resilience studies
• Cognitive and memory function models
• Inflammatory and neuroimmune research
• Fatigue and mood disorder investigations

Synthesis and Quality Control:

• Manufactured using solid-phase peptide synthesis (SPPS)
• HPLC purified to ≥98%
• Identity confirmed by Mass Spectrometry (MS)

Product Details:

• Form: Lyophilized acetate salt
• Appearance: White to off-white powder
• Supplied in: 3mL sterile vial

Solubility & Reconstitution:
Selank Acetate is soluble in sterile water, dilute acetic acid, or aqueous buffers at pH 5–7.

• Swirl gently to dissolve; avoid foaming or oxidation
• Stable in mild acidic conditions; avoid high pH

Storage & Handling:

• Store lyophilized powder at –20°C, protected from light and moisture
• After reconstitution, refrigerate at 2–8°C for up to 30 days
• For long-term storage, aliquot and freeze at –20°C
• Avoid repeated freeze-thaw cycles

Disclaimer:
For research use only. Not intended for human or veterinary use. Not for diagnostic or therapeutic applications.