Description
GHRP-6 Acetate
Chemical Name: Growth Hormone Releasing Peptide-6 (GHRP-6) Acetate
Molecular Formula: CββHβ
βNββOβ
Molecular Weight: ~873.01 g/mol
CAS Number: 87616-84-0
Sequence:
His-D-Trp-Ala-Trp-D-Phe-Lys-NHβ
Structural Characteristics:
GHRP-6 is a synthetic hexapeptide and potent agonist of the ghrelin receptor (GHS-R1a). It stimulates endogenous growth hormone release through a mechanism independent of GHRH. Compared to GHRP-2, GHRP-6 is also known to enhance appetite via hypothalamic activity.
Mechanism of Action (Research Context):
GHRP-6 binds to the ghrelin receptor to promote GH secretion and influence appetite-regulating pathways. Research applications include:
- GH release and endocrine axis research
- Cachexia, muscle wasting, and metabolic syndrome models
- Appetite stimulation and energy homeostasis investigations
Synthesis and Quality Control:
- Produced via solid-phase peptide synthesis (SPPS)
- Purified to β₯98% by HPLC
- Identity confirmed by Mass Spectrometry (MS)
Product Details:
- Form: Lyophilized acetate salt
- Appearance: White to off-white powder
Solubility:
GHRP-6 Acetate is soluble in sterile water, dilute acetic acid, or aqueous buffers at pH 5β7.
Storage & Handling:
- Store lyophilized powder at β20Β°C, protected from light and moisture.
- After reconstitution, refrigerate at 2β8Β°C for up to 30 days.
- For long-term storage, aliquot and freeze at β20Β°C.
- Avoid repeated freeze-thaw cycles.
Disclaimer:
For research use only. Not intended for human or veterinary use. Not for diagnostic or therapeutic applications.
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