Semaglutide Acetate – 10mg

Description

Semaglutide Acetate

Chemical Name: Semaglutide Acetate
Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉ · xC₂H₄O₂
Molecular Weight: ~4113.58 g/mol
CAS Number: 910463-68-2

Sequence:
H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-Cys-Asn-Ala-Ile-His-Ala-Gly-Gln-Leu-Ser-Ala-Arg-Leu-NH₂ (modified with a C18 fatty diacid at Lys26 via a gamma-Glu-2xOEG linker)

Product Overview:
Semaglutide Acetate is a synthetic GLP-1 receptor agonist peptide modified with a C18 fatty acid chain to enhance albumin binding and extend half-life. It plays a key role in research focused on glucose regulation, insulin secretion, and metabolic control.

Research Applications:

• Glucose regulation and insulin response
• β-cell function enhancement
• Appetite suppression and satiety
• Metabolic syndrome and obesity studies

Quality Assurance:

• Purity: ≥98% (HPLC)
• Synthesis method: Solid-phase peptide synthesis (SPPS) and lipidation
• Verified by Mass Spectrometry (MS), Peptide Content Analysis, and optional Endotoxin Testing (LAL)

Form: Lyophilized acetate salt
Appearance: White to off-white powder

Solubility:
Soluble in bacteriostatic water and other aqueous buffers at pH 5.0–7.0. Gentle swirling is sufficient for dissolution.

Storage & Handling:
Store lyophilized powder at –20°C, protected from moisture and light. After reconstitution, store at 2–8°C for up to 60 days if sterile. For extended storage, aliquot and freeze at –20°C. Avoid repeated freeze-thaw cycles.

Disclaimer:
For research use only. Not for human or veterinary use. Not for diagnostic or therapeutic applications.