NAD+ 500mg
$113.94
NAD⁺ (Nicotinamide Adenine Dinucleotide, Oxidized Form) is a redox-active pyridine nucleotide central to energy metabolism, oxidative phosphorylation, and sirtuin-mediated gene regulation. As a universal electron carrier and essential coenzyme for dehydrogenases and ADP-ribosyltransferases, NAD⁺ plays a pivotal role in cellular respiration, DNA repair, and metabolic signaling pathways relevant to aging, stress response, and mitochondrial function.
Supplied as a lyophilized salt, NAD⁺ is optimized for sterility, stability, and extended shelf life. Provided in a 10mL vial, this oxidized dinucleotide is suited for research into NAD⁺/NADH redox cycling, SIRT1 activation, and the regulation of cellular energy homeostasis.
Solubility: NAD⁺ is soluble in sterile water, dilute acetic acid, or aqueous buffers at pH 5–7.
For laboratory research use only. Not for human or veterinary applications.
Description
NAD⁺
Chemical Name: Nicotinamide Adenine Dinucleotide (Oxidized Form)
Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
Molecular Weight: ~663.43 g/mol
CAS Number: 53-84-9
Structure Overview:
NAD⁺ is a coenzyme composed of two nucleotides joined through phosphate groups: one containing an adenine base and the other nicotinamide. It plays a pivotal role in cellular energy metabolism and redox reactions, acting as a universal electron carrier in oxidation-reduction processes.
Mechanism of Action (Research Context):
NAD⁺ is involved in a wide range of biological pathways and is a central molecule in:
- Mitochondrial energy production (ATP synthesis)
- Sirtuin activation and aging research
- DNA repair via PARP enzyme activity
- Cellular stress responses and redox balance
- Neurodegeneration and metabolic syndrome models
Synthesis and Quality Control:
- Produced via biosynthetic or enzymatic routes
- Purified to ≥98% by HPLC
- Verified by Mass Spectrometry (MS) and NMR
Product Details:
- Form: Lyophilized powder
- Appearance: White to off-white powder
Solubility:
NAD⁺ is highly soluble in sterile water or aqueous buffers. Prepare fresh solutions as NAD⁺ can degrade in solution over time.
Storage & Handling:
- Store lyophilized powder at –20°C, protected from moisture and light
- After reconstitution, store at 2–8°C and use promptly
- For long-term storage, aliquot and freeze at –20°C
- Avoid repeated freeze-thaw cycles
Disclaimer:
For research use only. Not intended for human or veterinary use. Not for diagnostic or therapeutic applications.
Additional information
| Weight | .06 lbs |
|---|---|
| Dimensions | .5 × .5 × 1 in |
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