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CJC-1295 with DAC Acetate
$49.90
CJC-1295 with DAC Acetate is a synthetic 30-amino acid analog of growth hormone-releasing hormone (GHRH) incorporating a maleimidopropionyl linker known as the Drug Affinity Complex (DAC). This modification enables covalent binding to serum albumin, dramatically extending the peptide’s half-life and supporting prolonged elevation of circulating growth hormone and IGF-1 levels. CJC-1295 with DAC is developed for research into sustained somatotropic stimulation, anabolic signaling, and endocrine regulation.
Supplied as a lyophilized acetate salt, CJC-1295 with DAC Acetate is optimized for sterility, stability, and extended shelf life. Provided in a 3 mL vial, this long-acting GHRH analog is suited for studies requiring extended GH exposure, reduced dosing frequency, and continuous IGF-1 modulation.
Solubility: CJC-1295 with DAC Acetate is soluble in sterile water, dilute acetic acid, or aqueous buffers at pH 5–7.
For laboratory research use only. Not for human or veterinary applications.
Description
CJC-1295 with DAC Acetate
(Drug Affinity Complex)
Chemical Name: CJC-1295 with Drug Affinity Complex (DAC) Acetate
Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
Molecular Weight: ~3367.88 g/mol
CAS Number: 863288-34-0
Sequence:
Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Gly-Ser-Asn-Gln-Gln-Gly-Gly-Gly-Gly
(C-terminal modified with a reactive linker for DAC conjugation)
Structural Characteristics:
CJC-1295 with DAC is a tetrasubstituted analog of growth hormone-releasing hormone (GHRH 1–29) that has been covalently linked to a Drug Affinity Complex (DAC). This modification enables reversible binding to serum albumin, significantly extending its plasma half-life and allowing for sustained stimulation of endogenous growth hormone release.
Mechanism of Action (Research Context):
By binding the GHRH receptor, CJC-1295 with DAC promotes long-lasting elevations in growth hormone (GH) and IGF-1 levels. Research applications include:
- Muscle growth, repair, and hypertrophy models
- Anti-aging and regenerative studies
- Body composition and fat metabolism research
- Endocrine axis and GH pulsatility investigations
Synthesis and Quality Control:
- Manufactured via solid-phase peptide synthesis (SPPS)
- Purified to ≥98% by HPLC
- Verified by Mass Spectrometry (MS)
Product Details:
- Form: Lyophilized acetate salt
- Appearance: White to off-white powder
- Supplied in: 3mL sterile vial
Solubility & Reconstitution:
Soluble in sterile water, dilute acetic acid, or aqueous buffers at pH 5–7.
- Use mildly acidic diluent (pH 5.0–6.5) for optimal stability
- Avoid prolonged air exposure and high pH conditions
- Swirl gently to dissolve
Storage & Handling:
- Store lyophilized powder at –20°C, protected from moisture and light
- After reconstitution, store refrigerated at 2–8°C for up to 30 days
- For extended use, aliquot and freeze at –20°C
- Avoid repeated freeze-thaw cycles
Disclaimer:
For research use only. Not for human or veterinary use. Not for diagnostic or therapeutic applications.
Additional information
| Weight | .06 lbs |
|---|---|
| Dimensions | .5 × .5 × 1 in |
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