Tesamorelin Acetate
$43.10
Tesamorelin Acetate is a 44-amino acid, synthetic growth hormone-releasing hormone (GHRH) analog engineered for research into lipodystrophy, metabolic disorders, and growth hormone (GH) secretagogue pathways. This peptide features a trans-3-hexenoyl modification at the N-terminus to enhance proteolytic stability and bioavailability, supporting long-acting GHRH receptor agonist studies.
Supplied as a lyophilized acetate salt, Tesamorelin Acetate is optimized for sterility, stability, and extended shelf life. Provided in a 3mL vial, this stabilized GHRH analog is ideal for studies investigating GH pulsatility, IGF-1 regulation, and metabolic modulation.
Solubility: Tesamorelin Acetate is soluble in sterile water, dilute acetic acid, or aqueous buffers at pH 5–7.
For laboratory research use only. Not for human or veterinary applications.
Description
Tesamorelin Acetate
Chemical Name: Tesamorelin Acetate
Molecular Formula: C₂₂₁H₃₆₆N₇₂O₆₇S
Molecular Weight: ~5135.9 g/mol
CAS Number: 218949-48-5
Sequence:
H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Gly-Ser-Asn-Gln-Gln-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Lys-Lys-Arg-Arg-Gln-Gln-Gly-Gly-Ser-Asn-Gln-Gln-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-NH₂
Structural Characteristics:
Tesamorelin is a synthetic, stabilized analog of growth hormone-releasing hormone (GHRH 1–44) with a trans-3-hexenoic acid modification at the N-terminal position for enhanced stability. It binds to the GHRH receptor, stimulating growth hormone release in a pulsatile fashion and is utilized in metabolic and endocrine research.
Mechanism of Action (Research Context):
Tesamorelin acts as a GHRH receptor agonist, promoting endogenous growth hormone secretion. Research applications include:
- Studies on visceral adipose tissue reduction
- Lipid metabolism and body composition models
- GH pulsatility and metabolic axis investigations
Synthesis and Quality Control:
- Synthesized via solid-phase peptide synthesis (SPPS)
- Purified to ≥98% by HPLC
- Verified by Mass Spectrometry (MS)
Product Details:
- Form: Lyophilized acetate salt
- Appearance: White to off-white powder
Solubility:
Tesamorelin Acetate is soluble in sterile water, dilute acetic acid, or aqueous buffers at pH 5–7.
Storage & Handling:
- Store lyophilized powder at –20°C, protected from light and moisture
- After reconstitution, store at 2–8°C for up to 30 days
- For extended storage, aliquot and freeze at –20°C
- Avoid repeated freeze-thaw cycles
Disclaimer:
For research use only. Not intended for human or veterinary use. Not for diagnostic or therapeutic applications.
Additional information
| Weight | .06 lbs |
|---|---|
| Dimensions | .5 × .5 × 1 in |
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