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Survodutide Acetate – 10mg
$121.88
Survodutide Acetate is a synthetic peptide dual agonist targeting the glucagon receptor (GCGR) and glucagon-like peptide-1 receptor (GLP-1R), engineered for research into obesity, metabolic syndrome, and energy expenditure modulation. By combining glucagon-mediated thermogenesis with GLP-1–driven appetite suppression and glucose regulation, Survodutide supports studies exploring multi-pathway approaches to weight loss, insulin sensitivity, and lipid metabolism.
Supplied as a lyophilized acetate salt, Survodutide Acetate is optimized for sterility, stability, and extended shelf life. Provided in a 3 mL vial, this dual receptor agonist is ideal for investigations into incretin–glucagon synergy, metabolic rate enhancement, and body composition regulation.
Solubility: Survodutide Acetate is soluble in sterile water, dilute acetic acid, or aqueous buffers at pH 5–7.
For laboratory research use only. Not for human or veterinary applications.
Description
Survodutide Acetate
Chemical Name: Survodutide Acetate
Molecular Formula: C₂₉₄H₄₅₅N₇₉O₈₃
Molecular Weight: ~6485.3 g/mol
CAS Number: 2381089-83-2
Sequence:
H-His-Ser-Gln-Gly-Thr-Phe-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Gly-Glu-Gly-Val-Gly-Gly-Gly-Gly-Cys-Lys(AEEA-C20 diacid)-Ala-Ala-Ala-Glu-Gly-Glu-Leu-Gln-Gly-Ala-Leu-Glu-Gly-Gly-Gly-Thr-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-Arg-Gly-Cys-His-Ala-Ile-Ala-Asp-Leu-Glu-Ser-Leu-Gln-Gly-Glu-Leu-Ser-Ser-Leu-Gln-Ser-Glu-Leu-Ser-Glu-Gly-Ala-Gln-Ala-Lys-NH₂
Structural Characteristics:
Survodutide is a 31-amino acid synthetic peptide analog functioning as a dual agonist at the GLP-1 and glucagon receptors. It is lipidated at a specific lysine residue via an AEEA linker to a C20 fatty diacid, enhancing albumin binding and extending plasma half-life. This modification supports prolonged receptor activation for metabolic research applications.
Mechanism of Action (Research Context):
Survodutide has been studied for its dual receptor activation profile, with potential research applications in:
- Appetite regulation and satiety signaling
- Energy expenditure and fat oxidation models
- Glycemic control and insulin sensitivity studies
- Non-alcoholic fatty liver disease (NAFLD) and obesity research
Synthesis and Quality Control:
- Produced via solid-phase peptide synthesis (SPPS) with site-specific lipidation
- Purified to ≥98% by HPLC
- Identity confirmed by Mass Spectrometry (MS)
Product Details:
- Form: Lyophilized acetate salt
- Appearance: White to off-white powder
- Supplied in: 3mL sterile vial
Solubility & Reconstitution:
Soluble in sterile water, dilute acetic acid, or aqueous buffers at pH 5–7.
- Swirl gently to dissolve; avoid vigorous shaking
- Protect from high pH and oxidative conditions
Storage & Handling:
- Store lyophilized powder at –20°C, protected from light and moisture
- After reconstitution, refrigerate at 2–8°C for up to 30 days
- For extended storage, aliquot and freeze at –20°C
- Avoid repeated freeze-thaw cycles
Disclaimer:
For research use only. Not for human or veterinary use. Not for diagnostic or therapeutic applications.
Additional information
| Weight | .06 lbs |
|---|---|
| Dimensions | .5 × .5 × 1 in |
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